Mabuhay Gardens was originally a Filipino restaurant and club owned by Ness Aquino that featured many Filipino Superstars including Miss Amapola, the singing sensation who later co-hosted with Ness Aquino on her weekly "Amapola Presents Show" on KEMO-TV Channel 20. Located at 448 Broadway in the North Beach neighborhood of San Francisco, an area famous for its strip clubs. Rock promotor Dirk Dirksen rented out the club and began booking punk bands there, and the venue soon became one of the centers of punk rock in San Francisco in the late 1970s and early 1980s. Numerous bands, including the Dictators (1976), Dead Kennedys, Metallica, Romeo Void, Black Flag, The Nuns, The Avengers, The Damned, DEVO, Iggy Pop, The Ramones, Hüsker Dü, D.O.A., The Screamers — virtually every band from the early days of punk would play there. According to the intro crawl of the Dead Kennedys' Live at DMPO's on Broadway video, Whoopie Goldberg also made early appearances at the venue. Dirk Dirsen who wrote and directed "Amapola Presents Show" featured several of the bands in tandem with Fab Mab.

The club shut down in 1986. It is now a yuppie bar.

The upstairs of the building housed the just-as-legendary DMPO's on Broadway.